Topical Collagen Treatment on a Diabetic Patient With A Non-Healing Post Amputation Wound

Taken From: 1996 Symposium on Advanced Wound Care and Medical Research Forum on Wound Repair

A case study of a 44 year old insulin dependent diabetic female with peripheral neuropathy and no other significant medical history, who has presented with a left forefoot metatarsal amputation wound, which has been non-healing for 2 months. Recommendation by surgeon has been for patient to see Plastic Surgeon for skin graft to be done. Patient referred to wound center by private internist for consult related to non-healing wound. Patient presented with left lower leg edematous and oral temperature of 99 degrees Fahrenheit. Patient admitted to hospital for cellulitis of left leg and ulceration. Non-invasive vascular studies done: venous examination show no evidence of deep venous thrombosis and TcPO2 64. Wound care treatment to date was wet-to-dry sterile dressing using normal saline. Initial wound size (length x width) 190 mm x 80 mm. Treatment with Kollagen / Medifil (tm) was initiated with weekly wound measurements, tracings, and photographs obtained. Within one week, as seen with other wounds using Kollagen, granulation tissue and contraction of wound edges was noted. After discharge from hospital, patient received daily wound care by home health agency and weekly visits to the wound care center. At week 8, a reduction of 45% of the wound size was documented. The efficacy of topical collagen on non-healing wound was demonstrated.

Addendum: 5/17/96. Closure of dorsal wound surface achieved. Patient then evaluated for orthotics to help patient ambulate correctly.

Please feel free to contact BioCore Inc. at 1-800-577-4801 if you have any questions about Medifil (tm) product.

Return to Main Page, Wound Care Institute Newsletter, Fall 1996